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Table 1 The baseline characteristics of the IPF patients

From: Inhibition of DLK1 regulates AT2 differentiation and alleviates established pulmonary fibrosis by upregulating TTF-1/CLDN6

Characteristics

Patient 1

Patient 2

Patient 3

Patient 4

Patient 5

Patient 6

Patient 7

Patient 8

Patient 9

Patient 10

Patient 11

Sex

M

F

M

F

M

M

M

F

M

M

M

Age(years)

66

57

67

63

64

72

67

40

70

62

49

BMI(Kg/m2)

20.45

19.7

23.7

23.7

25.8

23.9

27.3

22.98

23.34

17.81

28.28

Smoking status

Current

Never

Former

Never

Former

Never

Current

Never

Never

Former

Current

Antibiotic application

No

No

Yes

Yes

Yes

Yes

Yes

Yes

Yes

No

Yes

Family history of IPF

Unknown

Yes

Unknown

Unknown

Unknown

Unknown

Unknown

Yes

Unknown

Unknown

No

VC(%pro)

45

38

71

68

77

72

54

33

58

65

48

FVC(L)

1.39

1.01

1.98

1.46

2.84

2.17

1.85

1.07

1.92

3.07

1.90

FEV1 (L)

1.35

0.95

1.98

1.30

2.24

1.81

1.55

1.00

1.72

2.99

1.68

FEV1/FVC(%)

97.00

93.43

100.00

88.90

78.82

83.67

83.79

93.04

89.41

97.41

88.36

MEF25(% pro)

57

47

229

52

45

60

45

43

107

179

49

MEF50(% pro)

87

49

122

94

58

87

63

102

73

147

66

MEF75(%pro)

151

58

88

99

90

106

107

91

57

107

65

TLC(L)

3.02

3.11

3.77

2.38

4.64

3.66

3.08

2.05

3.93

5.74

3.16

RV (L)

1.42

2.12

1.66

1.00

1.77

1.54

1.25

0.89

1.78

2.39

1.20

RV/TLC(%)

47.00

68.13

44.02

41.79

38.28

42.06

40.72

43.56

45.39

41.67

38.18

MV (L/min)

17.30

11.60

40.64

8.18

12.61

14.04

16.67

12.44

17.25

13.02

19.72

DLCO(%pro)

45

38

23

47

23

61

26

24

34

23

49

Comorbidities

Hypertension

/

Hypertension; Diabetes

Liver disease

Coronary heart disease

/

Diabetes

Hyperlipemia

/

Hypertension

Hyperlipemia

/