Fig. 7
From: SERPINB10 promotes macrophage M2 polarization and airway inflammation in asthma

Diagram of the mechanisms by which SERPINB10 promotes macrophage M2 polarization. SERPINB10 suppresses IL-4Rα degradation and upregulates downstream Stat6 and Akt phosphorylation, thereby promoting macrophage M2 polarization in asthma