Table 1 Baseline characteristics of subjects: individuals with chronic obstructive pulmonary disease (COPD), acute exacerbation of COPD (AECOPD) and controls
Variable | COPD (n = 16) n (%) or mean (± SD) | AECOPD (n = 11) n (%) or mean (± SD) | p-value | Controls |
|---|---|---|---|---|
Age (years) | 62.6 (3.5) | 66.5 (4.9) | 0.376 | 42.1 (range 29–63) |
Sex (n) | 0.900 | |||
Male | 4(33) | 3(27) | 13 (56) | |
Female | 12(67) | 8(73) | 10 (44) | |
Race (n) | 0.080 | |||
White | 16 (100) | 9 (82) | 22 (96) | |
Black | 0 | 2 (18) | 0 | |
Asian | 0 | 0 | 1 (4) | |
Current Smokers (n) | 4 (25.0) | 3 (27.0) | 0.900 | n/s |
Total pack years (mean) | 42.929 (9.3) | 46.8 (26.4) | 0.751 | n/s |
Forced Vital Capacity (FVC) (L) | 2.29 (0.8) | 1.96 (0.8) | 0.355 | n/s |
Forced Expiratory Volume in one second (FEV1) (L) | 1.46 (0.7) | 0.88 (0.4) | 0.029 | n/s |
FEV1/FVC (%) | 51.5 (12.7) | 40.0 (17.92) | 0.094 | n/s |
Diffusing Capacity (DLCO) (ml/min/Hg) | 15.87 (5.6); n = 8 | 9.66 (4.8); n = 6 | 0.050 | n/s |
Eosinophils (cells/µl) | 190.7 (98.6) | * | n/a | n/s |