Fig. 2
From: Multi-omics characterization of early chronic obstructive pulmonary disease
Proteomic signatures of biological ECOPD. (A) Overview of the proteomic profiles of CPHS populations. Protein abundances from plasma of ECOPD (red) and HC (blue) are shown, with quantification using log2 transformed quantile normalized intensity. The highest- and lowest-abundance proteins are highlighted in the boxed region. (B) Expression levels of KRT13 and DCD in both the CPHS cohort and validation cohort. (C) Expression changes of CLU, AZGP1 and F2 in HC and ECOPD in the CPHS cohort. (D) Validation of observed protein expression changes in the independent validation cohort