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Table 2 Association between ARBs use and risk of lung cancer

From: Angiotensin receptor blockers use and lung cancer risk in Chinese patients with chronic obstructive pulmonary disease: a population-based cohort study

Models

Binary ARBs exposure

Cumulative Years of Use

HR (95% CI)

P value

HR (95% CI)

P value

Model1

1.06(0.87,1.29)

0.5713

0.95(0.92,0.98)

0.0046

Model2

1.03(0.84,1.25)

0.7742

0.95(0.92,0.98)

0.0039

Model3

1.00(0.82,1.23)

0.9777

0.94(0.91,0.98)

0.0012

Model4

0.95(0.77,1.16)

0.5907

0.93(0.90,0.97)

0.0002

  1. Model 1 estimated crude HR; model 2 was adjusted for age and gender; model 3 was further adjusted for incorporates comorbidities; model 4 was further adjusted for education levels, smoking status, drinking status, COPD exacerbation status, the number of hospital admissions, and comedications