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Fig. 3 | Respiratory Research

Fig. 3

From: Dysregulated metabolic pathways of pulmonary fibrosis and the lipids associated with the effects of nintedanib therapy

Fig. 3

(A) The OPLS-DA of PF patients and HC subjects. (B) VIP scores for extracted lipids that help discriminate between PF patients and HC subjects. The vertical axis indicates the lipids, and the horizontal axis indicates the VIP scores. (C) List of lipids with both a valuable VIP score and logFC value. n/d: not detected. (D) Distribution of each lipid in the top 3 ranked lipid species indicated using box-and-whisker plots. The top 3 ranked lipids by VIP score were down-regulated in PF, whereas the up-regulated lipids exhibited medium to low VIP scores

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