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Fig. 6 | Respiratory Research

Fig. 6

From: ETS2 aggravate allergic airway inflammation by regulating ANT2-mediated cytosolic mitochondrial DsRNA levels

Fig. 6

ETS2 deficiency results in suppressed ANT2 expression. (A) The volcano plots of DEGs in ETS2fl/fl compared to ETS2fl/fl;Scgb1a1-IRES-cre mice with OVA-induced asthma. (B) Input DEGs into ChEA3 (https://maayanlab.cloud/chea3) to obtain the downstream of ETS2. (c, d) Decrease epithelial ANT2 mRNA (C) and protein (D, E) expression in mice with genetically modified epithelial cells (ETS2fl/fl;Scgb1a1-IRES-cre mice) with asthma compared to ETS2fl/fl.**P < 0.01 versus ETS2fl/fl

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Respiratory Research

ISSN: 1465-993X

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