Skip to main content
Fig. 5 | Respiratory Research

Fig. 5

From: ETS2 aggravate allergic airway inflammation by regulating ANT2-mediated cytosolic mitochondrial DsRNA levels

Fig. 5

ETS2 derives mitochondrial dsRNA into the cytosol. (A) Relative mitochondrial RNA levels in the cytosol of ETS2-overexpressing (OE),-knockdown (KD) or the vector-control (CON) cells. (B) Confocal examination of dsRNA levels in ETS2-overexpressing (OE),-knockdown (KD) or the vector-control (CON) cells with J2 antibody. (C) Quantification of the relative dsRNA fluorescent signals in B. (D) Relative ISG15,MDA5,RIG-1 mRNA levels in ETS-overexpressing (OE),-knockdown (KD) or the vector-control (CON) cells. (E). ISG15,MDA5,RIG-1and ETS2 protein levels in ETS-overexpressing (OE), -knockdown (KD) or the vector-control (CON) cells. GAPGH was used as a loading control

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us