Table 2 Characteristics of biosensors applied in PH
From: Advances and applications of biosensors in pulmonary hypertension
Biosensors | Basic principle | Core technologies | Detection parameters |
|---|---|---|---|
CardioMEMS | A percutaneously implanted pressure biosensor in the pulmonary artery branch monitors hemodynamic parameters | Biocompatible materials, miniaturized circuitry, wireless power transfer | PA waveform、HR、PASP、PADP、mPAP |
BNP biosensors | The concentration of BNP in biological samples via biosensor | Electrochemical or optical sensing technology, nanomaterial signal amplification | BNP concentration |
miRNA biosensors | Specific disease-associated miRNAs detected via biosensors | CRISPR/Cas-based recognition, SPR, nanopore sequencing | Specific miRNA expression levels |
e-Nose | Detection of specific gas biomarkers via biosensors | Sensor array, pattern recognition algorithm | Non-invasive gas biomarkers |
Wireless wearable biosensor | A multi-module integrated biosensor system for comprehensive assessment of physical mobility and cardiac function | Wireless communication technology, IMU, biosensing technology | HR、HRV、RR、SpO2、TFC、BP |