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Table 3 Clinicopathological characteristics of the patients with ARDS based on survival

From: MFGE8 regulates the EndoMT of HLMECs through the BMP signaling pathway and fibrosis in acute lung injury

Characteristic

Survivors, n = 33

Non-survivors, n = 11

Age, years

67.03 ± 9.30

71.36 ± 9.29

Sex, male/female

20/13

3/8

BMI, kg/m2

23.4 ± 1.32

23.34 ± 1.58

PaO2/FiO2, mmHg

95.30 ± 14.32

88.54 ± 15.11

White blood cell count, x109/l

17.44 ± 5.23

14.43 ± 5.26

C-reactive protein, mg/l

30.51 ± 11.75

31.02 ± 1.02

Procalcitonin, ng/ml

2.75 ± 1.35

3.06 ± 1.27

MFGE8, pg/ml

65.6 ± 18.94

45.09 ± 10.79a

Comorbidity, n

  

Obstructive airway disease

10

6

Hypertension

14

4

Diabetes

6

3

Cardiovascular disease

6

3

Cerebrovascular accident

1

0

Hematological disease

1

1

Chronic renal failure

0

2

Cancer history

5

2

Pulmonary etiology of ARDS

20 (60.60%)

7 (63.63%)

Pulmonary infection

13 (39.39%)

5 (45.45%)

Aspiration

7 (21.21%)

2 (18.18%)

Extrapulmonary etiology of ARDS

13 (39.39%)

4 (36.36%)

Sepsis

8 (24.24%)

2 (18.18%)

Pancreatitis

5 (15.15%)

2 (18.18%)

  1. aP < 0.05 vs. healthy control. Data are presented as the mean ± SD. MFGE8, Milk Fat Globule Epidermal Growth Factor 8; ARDS, acute respiratory distress syndrome; PaO2, Partial Pressure of Oxygen; FiO2, Fraction of Inspiration O2