Fig. 1

The physico-chemical characterization of menthol-flavored JUUL aerosol exposures reveals high iron content. a Experimental scheme of the 60 days JUUL aerosol plus HDM exposures. b 60 days average exposure parameters measured daily inside the exposure chambers. Temperature and relative humidity were measured within the exposure chambers using a hydrometer. c Chemical profile of the JUUL menthol-flavored aerosol for propylene glycol, glycerin, nicotine, carbonyls and organic acids. The samples were collected at the Louisiana State University Inhalation Research Facility and were analyzed by Enthalpy Analytical (Durham, NC). d Menthol-flavored JUUL aerosol particle size distribution measured with a scanning mobility particle sizer (SMPS). e Concentration of metals (Fe, Cr, Cu) found in the menthol-flavored JUUL aerosols. The samples were collected at the Louisiana State University Inhalation Research Facility and were analyzed by Eurofins (Liverpool, NY)