Table 1 Basic characteristics of the two cohorts
| Â | Takeda cohort (Healthy) | Kyoto-Himeji cohort (COPD) |
|---|---|---|
N | 194 | 199 |
COPD, n (%) | 0 (0.0%) | 100 (100.0%) |
Age, years | 51.3 (8.4) | 72.7 (8.2) |
Sex, Female, n (%) | 97 (50.0%) | 13 (6.5%) |
Height, cm | 164.2 (8.6) | 164.9 (7.0) |
BMI, kg/m2 | 22.5 (3.0) | 23.2 (3.7) |
Current smoker, n (%) | 0 (0.0%) | 50 (25.1%) |
Pack-years | 0 | 59.9 (30.5) |
FEV1, L | 2.90 (0.63) | 1.67 (0.67) |
FEV1 percent predicted, % | 101.0 (10.1) | 63.2 (22.4) |
FVC, L | 3.58 (0.78) | 3.10 (0.91) |
FVC percent predicted, % | 100.3 (10.1) | 89.6 (22.1) |
FEV1/FVC | 0.81 (0.05) | 0.53 (0.12) |
Wall area, mm2 | 21.4 (3.2) | 28.1 (4.8) |
LAV%, % | 1.8 (2.0) | 15.3 (12.6) |
LLN for ESMD, HU | Male 38.8, Female 33.4 | Â |
LLN for ESMA, cm2 | Male 28.6, Female 21.5 | Â |
ESMD < LLN, % |  | 80 (40.2%) |
ESMA < LLN, % |  | 59 (29.6%) |