Heme-induced lung injury in human precision cut lung slices: a new model for acute lung injury

Respiratory Research

Table 1 Clinical information from PCLS tissue donors

Donor No	Gender	Age (years)	Diagnosis	Smoking status	Methods and analysis
1	Female	71	NET	Unknown	XTT, ELISA
2	Male	74	NSCLC, squamous	Ex-smoker, 30 PY	ELISA, transcriptomics, proteomics
3	Male	73	NSCLC, squamous	Ex-smoker, 50 PY	ELISA
4	Male	62	Lung Metastasis	Non-smoker	XTT, ELISA
5	Male	73	Lung Metastasis	Ex-smoker, 50 PY	XTT, ELISA
6	Male	62	Lung Metastasis	Non-smoker	ELISA, transcriptomics, proteomics
7	Male	62	NSCLC, adenocarcinoma	Ex-smoker, 70 PY	ELISA, transcriptomics, proteomics
8	Female	54	NSCLC	Smoker, 30 PY	XTT, ELISA, LDH, transcriptomics, proteomics
9	Male	39	Congenital pulmonary airway malformation	Unknown	XTT, ELISA, LDH, transcriptomics, proteomics
10	Female	64	NSCLC, squamous	Smoker, 40 PY	XTT, ELISA, LDH, transcriptomics, proteomics
11	Female	67	B-Cell Lymphoma	Ex-smoker, 20 PY	ELISA, LDH, transcriptomics, proteomics
12	Male	77	NSCLC, squamous	Ex-smoker, 60 PY	ELISA, LDH, transcriptomics, proteomics
13	Male	73	NSCLC, squamous	Smoker, 100 PY	LDH, immunofluorescence
14	Male	67	NSCLC, adenocarcinoma	Smoker, 50 PY	LDH
15	Female	58	NSCLC, adenocarcinoma	Ex-smoker, 100 PY	LDH
16	Male	72	NET	Ex-smoker, 100 PY	Immunofluorescence
17	Female	62	NSCLC, adenocarcinoma	Non-smoker	Immunofluorescence
18	Female	64	NSCLC, adenocarcinoma	Smoker, 50 PY	Immunofluorescence
19	Female	47	NSCLC	Non-smoker	XTT, ELISA
20	Male	78	NSCLC, adenocarcinoma	Non-smoker	XTT, ELISA
21	Female	51	Lung metastasis	Unknown	XTT, ELISA

ELISA enzyme-linked immunosorbent assay, LDH lactate dehydrogenase, NET neuroendocrine tumour, NSCLC non-small cell lung cancer, PY pack years, XTT 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-carboxanilide-2H-tetrazolium

ISSN: 1465-993X