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Fig. 3 | Respiratory Research

Fig. 3

From: Molecular mechanisms and therapeutic targets of acute exacerbations of chronic obstructive pulmonary disease with Pseudomonas aeruginosa infection

Fig. 3

Weighted Gene Co-expression Network Analysis (WGCNA) in AECOPD with P. aeruginosa Infection. (A) Cluster dendrogram displaying modules of co-expressed proteins, identified by dynamic tree cut. (B) Heatmap showing the correlation between module eigengenes and sample traits, with correlation coefficients and p-values. (C) GO and KEGG pathway enrichment analyses for the yellow module, highlighted the critical roles of acute inflammatory responses. (D) Neutrophil extracellular trap formation and the Leukocyte transendothelial migration pathway were highlighted in the blue module. (E) The brown module’s exploration illuminated processes essential for maintaining structural and functional integrity under infection. (F) Analyses for the grey module, indicating cell mediated cytotoxicity

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Respiratory Research

ISSN: 1465-993X

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