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Table 2 Inflammatory positive cells in the bronchial mucosa of patients

From: Vascular remodeling and TSLP/angiogenin overexpression in severe mixed asthma

Cell counts mm2 lamina propria

CTRL

(N = 7)

All asthmatics

(N = 40)

Eosinophilic

(n = 19)

Mixed

(n = 21)

ECP+ (Bronchial eosinophils)

6.8 ± 5.5

35.1 ± 19.1#

41.1 ± 28.5#

37.7 ± 21.9#

NE+ (Bronchial neutrophils)

8.4 ± 3.3

56.2 ± 38.2##

23.3 ± 11.1#

91.1 ± 36.6****/####

CD4+ (Bronchial T helper lymphocytes)

4.2 ± 4.1

27.6 ± 17.9#

25.6 ± 20.1#

29.7 ± 16.0##

CD68+ (Bronchial macrophages)

137.2 ± 85.2

241.5 ± 177.5

281.8 ± 174.2

207.9 ± 178.0

Mast cells/tryptase+

36.7 ± 29.2

89.1 ± 111.6

78.0 ± 60.6

103.6 ± 152.5

  1. Continuous variables are presented as mean ± SD
  2. ***: p < 0.001 compared to Eosinophilic; #: p < 0,05, ##: p < 0,01; ####: p < 0,001 vs. CTRL