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Table 1 Baseline clinical characteristics of TPE and non-TPE patients

From: The large language model diagnoses tuberculous pleural effusion in pleural effusion patients through clinical feature landscapes

 

Level

Overall

Non-TPE

TPE

p value

n

 

163

54

109

 

GROUP (%)

0

54 (33.13)

54 (100.00)

0 (0.00)

< 0.0001

 

1

109 (66.87)

0 (0.00)

109 (100.00)

 

Gender (%)

0

39 (23.93)

15 (27.78)

24 (22.02)

0.5378

 

1

124 (76.07)

39 (72.22)

85 (77.98)

 

COHORT (mean (SD))

 

2018.859 (3.222)

2018.944 (3.123)

2018.817 (3.283)

0.8123

Age (%)

0

28 (17.18)

1 (1.85)

27 (24.77)

0.0006

 

1

135 (82.82)

53 (98.15)

82 (75.23)

 

CRP (%)

0

36 (22.09)

19 (35.19)

17 (15.60)

0.0084

 

1

127 (77.91)

35 (64.81)

92 (84.40)

 

D-dimer (%)

0

81 (49.69)

32 (59.26)

49 (44.95)

0.1205

 

1

82 (50.31)

22 (40.74)

60 (55.05)

 

Electrolytes_Chloride (%)

0

118 (72.39)

33 (61.11)

85 (77.98)

0.0374

 

1

45 (27.61)

21 (38.89)

24 (22.02)

 

Electrolytes_Osmolality (%)

0

81 (49.69)

20 (37.04)

61 (55.96)

0.035

 

1

82 (50.31)

34 (62.96)

48 (44.04)

 

Electrolytes_Phosphorus (%)

0

92 (56.44)

34 (62.96)

58 (53.21)

0.3106

 

1

71 (43.56)

20 (37.04)

51 (46.79)

 

Electrolytes_Calcium (%)

0

99 (60.74)

30 (55.56)

69 (63.30)

0.4337

 

1

64 (39.26)

24 (44.44)

40 (36.70)

 

Electrolytes_Natrium (%)

0

43 (26.38)

7 (12.96)

36 (33.03)

0.0109

 

1

120 (73.62)

47 (87.04)

73 (66.97)

 

Electrolytes_Potassium (%)

0

52 (31.90)

22 (40.74)

30 (27.52)

0.1271

 

1

111 (68.10)

32 (59.26)

79 (72.48)

 

Electrolytes_Magnesium (%)

0

32 (19.63)

16 (29.63)

16 (14.68)

0.0401

 

1

131 (80.37)

38 (70.37)

93 (85.32)

 

Electrolytes_Anion gap (%)

0

74 (45.40)

20 (37.04)

54 (49.54)

0.1796

 

1

89 (54.60)

34 (62.96)

55 (50.46)

 

CEA (%)

0

75 (46.01)

16 (29.63)

59 (54.13)

0.0053

 

1

88 (53.99)

38 (70.37)

50 (45.87)

 

NSE (%)

0

35 (21.47)

18 (33.33)

17 (15.60)

0.0167

 

1

128 (78.53)

36 (66.67)

92 (84.40)

 

Liver function_GGT (%)

0

119 (73.01)

34 (62.96)

85 (77.98)

0.065

 

1

44 (26.99)

20 (37.04)

24 (22.02)

 

Liver function_Carbon dioxide (%)

0

62 (38.04)

24 (44.44)

38 (34.86)

0.3103

 

1

101 (61.96)

30 (55.56)

71 (65.14)

 

Liver function_Total bile acids (%)

0

78 (47.85)

16 (29.63)

62 (56.88)

0.0019

 

1

85 (52.15)

38 (70.37)

47 (43.12)

 

Liver function_Total bilirubin (%)

0

43 (26.38)

17 (31.48)

26 (23.85)

0.3946

 

1

120 (73.62)

37 (68.52)

83 (76.15)

 

Liver function_Total protein (%)

0

145 (88.96)

53 (98.15)

92 (84.40)

0.0178

 

1

18 (11.04)

1 (1.85)

17 (15.60)

 

Liver function_Globulin (%)

0

98 (60.12)

37 (68.52)

61 (55.96)

0.1704

 

1

65 (39.88)

17 (31.48)

48 (44.04)

 

Liver function_Albumin/Globulin ratio (%)

0

82 (50.31)

30 (55.56)

52 (47.71)

0.4372

 

1

81 (49.69)

24 (44.44)

57 (52.29)

 

Liver function_Albumin (%)

0

75 (46.01)

31 (57.41)

44 (40.37)

0.0591

 

1

88 (53.99)

23 (42.59)

65 (59.63)

 

Liver function_Direct bilirubin (%)

0

138 (84.66)

39 (72.22)

99 (90.83)

0.0041

 

1

25 (15.34)

15 (27.78)

10 (9.17)

 

Liver function_Alkaline phosphatase (%)

0

67 (41.10)

14 (25.93)

53 (48.62)

0.0092

 

1

96 (58.90)

40 (74.07)

56 (51.38)

 

Liver function_ALT (%)

0

135 (82.82)

48 (88.89)

87 (79.82)

0.2207

 

1

28 (17.18)

6 (11.11)

22 (20.18)

 

Liver function_AST/ALT ratio (%)

0

51 (31.29)

12 (22.22)

39 (35.78)

0.1147

 

1

112 (68.71)

42 (77.78)

70 (64.22)

 

Liver function_AST (%)

0

45 (27.61)

20 (37.04)

25 (22.94)

0.0874

 

1

118 (72.39)

34 (62.96)

84 (77.06)

 

Liver function_Indirect bilirubin (%)

0

81 (49.69)

23 (42.59)

58 (53.21)

0.2671

 

1

82 (50.31)

31 (57.41)

51 (46.79)

 

Liver function_BUN (%)

0

30 (18.40)

12 (22.22)

18 (16.51)

0.5026

 

1

133 (81.60)

42 (77.78)

91 (83.49)

 

Liver function_Uric acid (%)

0

18 (11.04)

4 (7.41)

14 (12.84)

0.4372

 

1

145 (88.96)

50 (92.59)

95 (87.16)

 

Liver function_Creatinine (%)

0

29 (17.79)

14 (25.93)

15 (13.76)

0.0903

 

1

134 (82.21)

40 (74.07)

94 (86.24)

 

Liver function_LDH (%)

0

37 (22.70)

17 (31.48)

20 (18.35)

0.0919

 

1

126 (77.30)

37 (68.52)

89 (81.65)

 

Pleural fluid biochemistry_Total protein (%)

0

61 (37.42)

35 (64.81)

26 (23.85)

< 0.0001

 

1

102 (62.58)

19 (35.19)

83 (76.15)

 

Pleural fluid biochemistry_Albumin (%)

0

45 (27.61)

26 (48.15)

19 (17.43)

0.0001

 

1

118 (72.39)

28 (51.85)

90 (82.57)

 

Pleural fluid biochemistry_ADA (%)

0

55 (33.74)

42 (77.78)

13 (11.93)

< 0.0001

 

1

108 (66.26)

12 (22.22)

96 (88.07)

 

Pleural fluid biochemistry_Glucose (%)

0

100 (61.35)

25 (46.30)

75 (68.81)

0.0091

 

1

63 (38.65)

29 (53.70)

34 (31.19)

 

Coagulation profile_Prothrombin time (%)

0

27 (16.56)

14 (25.93)

13 (11.93)

0.0414

 

1

136 (83.44)

40 (74.07)

96 (88.07)

 

Coagulation profile_Thrombin time (%)

0

71 (43.56)

30 (55.56)

41 (37.61)

0.0448

 

1

92 (56.44)

24 (44.44)

68 (62.39)

 

Coagulation profile_INR (%)

0

48 (29.45)

23 (42.59)

25 (22.94)

0.016

 

1

115 (70.55)

31 (57.41)

84 (77.06)

 

Coagulation profile_APTT (%)

0

82 (50.31)

32 (59.26)

50 (45.87)

0.1491

 

1

81 (49.69)

22 (40.74)

59 (54.13)

 

Coagulation profile_Fibrinogen (%)

0

92 (56.44)

27 (50.00)

65 (59.63)

0.3175

 

1

71 (43.56)

27 (50.00)

44 (40.37)

 

ESR (%)

0

43 (26.38)

21 (38.89)

22 (20.18)

0.0182

 

1

120 (73.62)

33 (61.11)

87 (79.82)

 

Blood cell analysis_Neutrophil percentage (%)

0

129 (79.14)

34 (62.96)

95 (87.16)

0.0007

 

1

34 (20.86)

20 (37.04)

14 (12.84)

 

Blood cell analysis_Neutrophil count (%)

0

101 (61.96)

20 (37.04)

81 (74.31)

< 0.0001

 

1

62 (38.04)

34 (62.96)

28 (25.69)

 

Blood cell analysis_Monocyte percentage (%)

0

50 (30.67)

31 (57.41)

19 (17.43)

< 0.0001

 

1

113 (69.33)

23 (42.59)

90 (82.57)

 

Blood cell analysis_Monocyte count (%)

0

136 (83.44)

40 (74.07)

96 (88.07)

0.0414

 

1

27 (16.56)

14 (25.93)

13 (11.93)

 

Blood cell analysis_Basophil percentage (%)

0

144 (88.34)

49 (90.74)

95 (87.16)

0.6803

 

1

19 (11.66)

5 (9.26)

14 (12.84)

 

Blood cell analysis_Basophil count (%)

0

82 (50.31)

24 (44.44)

58 (53.21)

0.375

 

1

81 (49.69)

30 (55.56)

51 (46.79)

 

Blood cell analysis_Eosinophil percentage (%)

0

134 (82.21)

37 (68.52)

97 (88.99)

0.0027

 

1

29 (17.79)

17 (31.48)

12 (11.01)

 

Blood cell analysis_Eosinophil count (%)

0

107 (65.64)

24 (44.44)

83 (76.15)

0.0001

 

1

56 (34.36)

30 (55.56)

26 (23.85)

 

Blood cell analysis_Large platelet ratio (%)

0

140 (85.89)

42 (77.78)

98 (89.91)

0.0636

 

1

23 (14.11)

12 (22.22)

11 (10.09)

 

Blood cell analysis_Red cell distribution width-SD (%)

0

64 (39.26)

13 (24.07)

51 (46.79)

0.0087

 

1

99 (60.74)

41 (75.93)

58 (53.21)

 

Blood cell analysis_Immature granulocyte percentage (%)

0

23 (14.11)

9 (16.67)

14 (12.84)

0.6739

 

1

140 (85.89)

45 (83.33)

95 (87.16)

 

Blood cell analysis_Immature granulocyte count (%)

0

145 (88.96)

44 (81.48)

101 (92.66)

0.0604

 

1

18 (11.04)

10 (18.52)

8 (7.34)

 

Blood cell analysis_Lymphocyte percentage (%)

0

51 (31.29)

24 (44.44)

27 (24.77)

0.0178

 

1

112 (68.71)

30 (55.56)

82 (75.23)

 

Blood cell analysis_Lymphocyte count (%)

0

107 (65.64)

26 (48.15)

81 (74.31)

0.0017

 

1

56 (34.36)

28 (51.85)

28 (25.69)

 

Blood cell analysis_Red cell distribution width-CV (%)

0

94 (57.67)

21 (38.89)

73 (66.97)

0.0012

 

1

69 (42.33)

33 (61.11)

36 (33.03)

 

Blood cell analysis_Hematocrit (%)

0

62 (38.04)

26 (48.15)

36 (33.03)

0.0891

 

1

101 (61.96)

28 (51.85)

73 (66.97)

 

Blood cell analysis_WBC (%)

0

84 (51.53)

24 (44.44)

60 (55.05)

0.2678

 

1

79 (48.47)

30 (55.56)

49 (44.95)

 

Blood cell analysis_Plateletcrit (%)

0

142 (87.12)

44 (81.48)

98 (89.91)

0.2065

 

1

21 (12.88)

10 (18.52)

11 (10.09)

 

Blood cell analysis_Platelet count (%)

0

146 (89.57)

47 (87.04)

99 (90.83)

0.6365

 

1

17 (10.43)

7 (12.96)

10 (9.17)

 

Blood cell analysis_Hemoglobin (%)

0

129 (79.14)

39 (72.22)

90 (82.57)

0.185

 

1

34 (20.86)

15 (27.78)

19 (17.43)

 

Lipid profile_LDL-C (%)

0

39 (23.93)

5 (9.26)

34 (31.19)

0.0038

 

1

124 (76.07)

49 (90.74)

75 (68.81)

 

Lipid profile_Total cholesterol (%)

0

84 (51.53)

21 (38.89)

63 (57.80)

0.0351

 

1

79 (48.47)

33 (61.11)

46 (42.20)

 

Lipid profile_Triglycerides (%)

0

133 (81.60)

34 (62.96)

99 (90.83)

< 0.0001

 

1

30 (18.40)

20 (37.04)

10 (9.17)

 

Lipid profile_HDL-C (%)

0

84 (51.53)

22 (40.74)

62 (56.88)

0.076

 

1

79 (48.47)

32 (59.26)

47 (43.12)

 

Random blood glucose (%)

0

91 (55.83)

27 (50.00)

64 (58.72)

0.375

 

1

72 (44.17)

27 (50.00)

45 (41.28)

 

Non-small cell lung cancer-associated antigen (%)

0

74 (45.40)

19 (35.19)

55 (50.46)

0.0937

 

1

89 (54.60)

35 (64.81)

54 (49.54)

 

Blood cell analysis_MCV (mean (SD))

 

90.702 (8.244)

91.048 (9.478)

90.530 (7.601)

0.7067

Blood cell analysis_MCH (mean (SD))

 

29.691 (2.952)

29.514 (2.925)

29.780 (2.974)

0.5896

Blood cell analysis_MCHC (mean (SD))

 

327.977 (12.777)

326.465 (13.344)

328.727 (12.482)

0.2889

Blood cell analysis_MPV (mean (SD))

 

9.956 (1.673)

9.919 (2.119)

9.974 (1.412)

0.8419

Blood cell analysis_PDW (mean (SD))

 

14.099 (3.036)

14.231 (3.341)

14.034 (2.887)

0.6976