Fig. 2

Pharmacological targeting of BRD4 ameliorated LPS/elastase-induced airway inflammation and emphysema. a Measurement of obstructive airflow limitation with FEV100/FVC (%), FRC, and TLC b Measurement of inflammatory cells, macrophages, neutrophils, and lymphocytes in BALF. c Representative H&E-stained pulmonary sections were isolated from different groups. Original magnifications 400 ×. d Semiquantitative analysis of airway inflammation. e Semiquantitative analysis of MLI, n = 5–10 mice per group. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001