Table 2 Functional classification of differentially expressed genes between the virus (Wuhan) infected only and the virus infected in the presence of MKGaA#49
Annotation cluster 1 | Enrichment Score: 9.7 | Count | P_Values | Benjamini |
|---|---|---|---|---|
UP_KW_BIOLOGICAL_PROCESS | Antiviral defense | 13 | 1.10E−15 | 2.70E−14 |
GOTERM_BP_DIRECT | Defense response to virus | 14 | 2.00E−15 | 7.70E−13 |
GOTERM_BP_DIRECT | Response to virus | 11 | 3.80E−14 | 7.50E−12 |
GOTERM_BP_DIRECT | Negative regulation of viral genome replication | 9 | 7.30E−14 | 9.60E−12 |
UP_KW_BIOLOGICAL_PROCESS | Innate immunity | 13 | 4.50E−10 | 5.60E−09 |
UP_KW_BIOLOGICAL_PROCESS | Immunity | 14 | 5.30E−07 | 4.40E−06 |
GOTERM_BP_DIRECT | Innate immune response | 10 | 6.90E−06 | 5.40E−04 |
GOTERM_MF_DIRECT | RNA binding | 6 | 2.80E−01 | 1.00E + 00 |
Annotation cluster 2 | Enrichment score: 5.63 | Count | P_Values | Benjamini |
|---|---|---|---|---|
KEGG_PATHWAY | Influenza A | 8 | 2.00E−07 | 1.60E−05 |
KEGG_PATHWAY | Hepatitis C | 7 | 2.60E−06 | 1.00E−04 |
KEGG_PATHWAY | Coronavirus disease—COVID-19 | 7 | 2.40E−05 | 6.40E−04 |
Annotation cluster 3 | Enrichment score: 3.72 | Count | P_Values | Benjamini |
|---|---|---|---|---|
GOTERM_CC_DIRECT | Cornified envelope | 7 | 4.10E−09 | 2.70E−07 |
GOTERM_BP_DIRECT | Keratinocyte differentiation | 6 | 3.20E−07 | 3.20E−05 |
INTERPRO | Cornifin (SPRR1) | 3 | 1.50E−05 | 1.70E−03 |
GOTERM_BP_DIRECT | Epidermis development | 5 | 3.70E−05 | 2.20E−03 |
GOTERM_BP_DIRECT | Peptide cross-linking | 4 | 4.00E−05 | 2.20E−03 |
GOTERM_BP_DIRECT | Keratinization | 5 | 4.70E−05 | 2.30E−03 |