Fig. 1

Volcano plots mapping out the distribution of differentially expressed genes (DEGs) in the fetal lungs following alcohol treatment compared with the controls (a) independent of sex (Control n = 10, Alcohol n = 10), (b) the male (Control n = 5, Alcohol n = 5), and (c) the female (Control n = 5, Alcohol n = 5). In all plots (A-C), red dots represent genes that are significantly upregulated following alcohol treatment compared to the Controls, blue dots indicate significantly downregulated genes following alcohol treatment compared to the Controls, and black dots represent genes that were not differentially expressed. Significance was established a priori at P < 0.05