Table 1 MR results for plasma and CSF proteins significantly associated with asthma after
From: Potential drug targets for asthma identified through mendelian randomization analysis
Tissue | Protein | UniProt ID | SNPa | Effect allele | OR (95% CI)b | P value | PVE | F statistics | Author |
|---|---|---|---|---|---|---|---|---|---|
Plasma | IL1R1 | P14778 | rs7588201 | A | 1.30 (1.20, 1.42) | 1.63E-09 | 1.21% | 39.3 | Emilsson |
Plasma | IL7R | P16871 | rs11957503 | G | 1.07 (1.04, 1.11) | 7.48E-06 | 8.69% | 94.74 | Suhre |
Plasma | ECM1 | Q16610;A0A140VJI7 | rs13294 | A | 1.03 (1.02, 1.05) | 2.92E-05 | 36.97% | 584.28 | Suhre |
Plasma | CD200R1 | Q8TD46 | rs6791672 | A | 1.18 (1.09, 1.27) | 1.74E-05 | 1.45% | 48.72 | Sun |
Plasma | ADAM19 | Q9H013 | rs7728609 | C | 0.87 (0.82, 0.92) | 6.17E-07 | 2.72% | 89.52 | Emilsson |
CSF | IL-6 sRa | P08887 | rs4129267 | T | 1.29 (1.15, 1.45) | 1.93E-05 | 36.34% | 476.66 | Yang |
CSF | Layilin | Q6UX15 | rs674230 | G | 0.61 (0.51, 0.73) | 1.14E-07 | 14.18% | 137.92 | Yang |