Skip to main content

Table 1 Allele frequencies in COPD and control subjects for SNPs

From: Interaction study of the effects of environmental exposure and gene polymorphisms of inflammatory and immune-active factors on chronic obstructive pulmonary disease

SNP (Gene)

Genotype

Control n (%)

Case n (%)

OR (95%CI)

P-value

rs1130864

G

896 (95.7)

853 (92.9)

Ref

0.02

(CRP)

A

40 (4.3)

65 (7.1)

1.77 (1.11–2.81)

rs2808630

T

800 (85.5)

787 (85.7)

Ref

0.93

(CRP)

C

136 (14.5)

131 (14.3)

0.99 (0.74–1.32)

rs1205

T

589 (62.9)

543 (59.2)

Ref

0.22

(CRP)

C

347 (37.1)

375(41.9)

1.14 (0.93–1.40)

rs4806606

A

810 (86.5)

813 (88.6)

Ref

0.04

(FCAR)

G

126 (13.5)

105 (11.4)

0.72 (0.53–0.98)

rs8112766

A

592 (63.3)

624 (68.0)

Ref

0.03

(FCAR)

G

344 (36.8)

294 (32.0)

0.79 (0.64–0.98)

rs4806608

A

814 (87.0)

824 (89.8)

Ref

0.06

(FCAR)

G

122 (13.0)

94 (10.2)

0.73 (0.53–1.01)

rs62123424

C

605 (64.6)

588 (64.1)

Ref

0.55

(FCAR)

T

331 (35.4)

330 (36.0)

0.94 (0.76–1.16)

rs7259090

G

830 (88.7)

834 (90.9)

Ref

0.13

(FCAR)

A

106 (11.3)

84 (9.2)

0.77(0.55–1.08)

rs11084376

C

657 (70.2)

670 (73.0)

Ref

0.18

(FCAR)

G

279 (29.8)

248 (27.0)

0.86 (0.68–1.07)

rs1865097

G

611 (65.3)

594 (64.7)

Ref

0.59

(FCAR)

A

325 (34.7)

324 (35.3)

0.94 (0.76–1.17)

rs2304225

C

812 (86.8)

794 (86.5)

Ref

0.98

(FCAR)

G

124 (13.3)

124 (13.5)

1.00 (0.74–1.35)

rs4656308

T

796 (85.0)

791 (86.2)

Ref

0.04

(FCGR2A)

C

140 (15.0)

127 (13.8)

0.74 (0.55–1.00)

rs4656309

C

469 (50.1)

474 (51.6)

Ref

0.05*

(FCGR2A)

T

467 (49.9)

444 (48.4)

0.81 (0.66–0.99)

rs1801274

A

613 (65.5)

604 (65.8)

Ref

0.55

(FCGR2A)

G

323 (34.5)

314 (34.2)

0.94 (0.76–1.16)

rs2165088

G

795 (84.9)

780 (85.0)

Ref

0.82

(FCGR2A)

A

141 (15.1)

138 (15.0)

0.97 (0.73–1.29)

rs4657040

T

794 (84.8)

778 (84.8)

Ref

0.44

(FCGR2A)

C

142 (15.2)

140 (15.3)

0.89 (0.67–1.19)

rs844

G

671 (71.7)

702 (76.5)

Ref

0.11

(FCGR2B)

A

265 (28.3)

216 (23.5)

0.83 (0.65–1.04)

rs16827592

T

761 (81.5)

730 (79.9)

Ref

0.48

(FCGR2B)

G

173 (18.5)

184 (20.1)

1.10 (0.85–1.42)

  1. Adjusted for age, Income, BMI, Education, History of RD, History of CVD, Smoking, Indoor fuel use, History of CHD/CHF, Straw burning outdoor
  2. The bolded content represents the distribution of each group, statistical results, and P-values of the statistically significant indicators
  3. "* indicates P<0.05