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Table 1 Baseline participant characteristics by ever-anemia status during study period

From: Longitudinal anemia status and risk for adverse outcomes in former smokers with COPD

 

Never Anemic

(N = 94)

Ever-Anemic

(N = 65)

P-value

Demographics

Age

66.9 (8.4)

66.0 (8.1)

0.49

Gender, N (% Female)

51 (54.3%)

31 (47.7%)

0.42

Race, N (% White)

60 (63.8%)

30 (46.2%)

0.03

Education, N (% Some college or above)

57 (60.6%)

31 (47.7%)

0.11

Pack-Years

50.0 (32.4)

48.7 (31.1)

0.80

BMI

31.3 (8.2)

32.0 (8.1)

0.61

ICS or LABA or LAMA, N (% Yes)

72 (76.6%)

49 (75.4%)

0.86

Comorbidities

Cardiovascular Disease, (#)

0.4 (0.7)

0.7 (0.9)

0.01

Chronic Kidney Disease, N (%)

2 (2.1%)

7 (10.8%)

0.02

Agatston score†

612.5 (1237.7)

923.8 (1521.4)

0.20

Agatston Categorical†, N (%)

  

0.04

0

23 (27.7%)

6 (11.8%)

 

0–99

24 (28.9%)

11 (21.6%)

 

100–399

11 (13.3%)

8 (15.7%)

 

≥ 400

25 (30.1%)

26 (51.0%)

 

Hemoglobin

14.2 (1.1)

12.0 (1.1)

< 0.01

Lung Function, Symptom Burden & Exacerbation History

FEV1% Predicted

53.8 (16.6)

48.2 (17.0)

0.04

COPD Assessment Test

17.7 (7,5)

19.0 (7.4)

0.32

St. George’s Respiratory Questionnaire

46 (18)

48 (15)

0.50

6-Minute Walk Distance (m)

256 (126)

206 (116)

0.08

Moderate/Severe Exacerbations in the Past 12 months, N (% Yes)

52 (55.9%)

36 (55.4%)

0.95

Supplemental oxygen use, N (% Yes)

18 (19.4%)

20 (30.8%)

0.10

  1. Abbreviations: BMI = body-mass index, FEV1 = forced expiratory volume in one second, ICS = inhaled corticosteroid, LABA = long-acting beta agonist, LAMA = long-acting muscarinic antagonist
  2. †n = 25 participants were missing observations for agatston