From: Diagnostic and prognostic implications of family history of fibrotic interstitial lung diseases
Overall N = 222 | Familial N = 104 | Sporadic N = 118 | p | OR | 95%CI | |
---|---|---|---|---|---|---|
Overall population | n = 94 | n = 41 | n = 53 | |||
UIP Non-UIP | 44 (47) 50 (53) | 26 (63) 15 (37) | 18 (34) 35 (66) | 0.005χ | 3.37 | 1.44–7.91 |
iUIP and non-UIP on HRCT | n = 74 | n = 37 | n = 37 | |||
UIP Non-UIP | 32 (43) 42 (57) | 23 (62) 14 (38) | 9 (24) 28 (76) | 0.001χ | 5.11 | 1.88–13.93 |
non-UIP on HRCT | n = 61 | n = 30 | n = 31 | |||
UIP Non-UIP | 19 (31) 42 (69) | 16 (53) 14 (47) | 3 (10) 28 (90) | < 0.001χ | 10.67 | 2.66 − 42.83 |