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Fig. 4 | Respiratory Research

Fig. 4

From: T follicular helper cell is essential for M2 macrophage polarization and pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension

Fig. 4

Inhibition of TFH cells alleviated pulmonary vascular remodelling in HPH. (a) Representative HE pathological staining of lung section (orginal magnification × 400). (b) The expression of α-SMA in pulmonary arteries was verified by immunofluorescence staining. (c-e) Changes of mean PAP, RV/(LV + S) ratio and PAMT. (f) The positive expression of α-SMA was analyzed by histogram.Values were means ± SD, n = 8. Comparisons were made using the one-way ANOVA with Bonferroni’s post hoc tests. Scale bar = 75 μm. *P < 0.05, ** P < 0.01

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