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Fig. 3 | Respiratory Research

Fig. 3

From: Inhibition of IRE1α/XBP1 axis alleviates LPS-induced acute lung injury by suppressing TXNIP/NLRP3 inflammasome activation and ERK/p65 signaling pathway

Fig. 3

4µ8C suppressed the activation of NLRP3 inflammasome in lungs of LPS-induced ALI murine model. (A) Representative immunohistochemical images of NLRP3 in lungs (magnification: 200×), scale bar = 50 μm. (B) Representative western blots of NLRP3, caspase-11, Pro-IL-1β and cleaved-IL-1β. (C-E) Densitometric analyses normalized to β-tubulin. Data are mean ± SEM, n = 4–6 for each group. *P < 0.05, **P < 0.01, ***P < 0.001

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Respiratory Research

ISSN: 1465-993X

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