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Fig. 2 | Respiratory Research

Fig. 2

From: Fisetin reduces ovalbumin-triggered airway remodeling by preventing phenotypic switching of airway smooth muscle cells

Fig. 2

Performing enrichment analysis, constructing PPI networks, and analyzing modules. (A) Venn diagram of fisetin targets, asthma-related genes, and ASMC-related genes. (B) Metascape bar graph of enriched terms showing the top 20 targets. The enhanced terms were prioritized according to p-values, with more vibrant colors representing smaller p-values. (C) Metascape visualization of the networks of the top 20 clusters, with each cluster distinguished by a unique color based on its cluster ID. Nodes with the same cluster ID exhibit stronger interconnections. (D) Construction of a PPI network for genes with increased expression. (E) The top 10 targets were ranked according to MCC, betweenness centrality, and degree, as performed using the plug-in of Cytoscape

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