- Note: Table color coding represents the severity of epithelial ulceration, inflammation, and fibrosis on a heat map ranging from green (less severe) to red (more severe). Epithelial ulceration and fibrosis were graded on a five-point scale: 0: 0%, 1: 1–25%, 2: 25–50%, 3: 50–75%, 4: 75–100%. Inflammation was graded on a three-point scale: 1: mild, 2: moderate, 3: severe.  Â