Table 1 Demographic and clinical characteristics of the study groups at inclusion
Variable | IPF (n = 20) | Controls (n = 15) | p value |
|---|---|---|---|
Demographics | |||
Age, years (IQR) | 78 (73–83) | 68 (58–72) | < 0.0001 |
Male, n (%) | 13 (65) | 7 (47) | 0.3 |
BMI, kg/m2 (IQR) | 26.4 (25.3–27.6) | 26.2 (24–28.9) | 0.6 |
Smoking habit | |||
Never, n (%) | 5 (25) | 8 (53) | 0.3 |
Former, n (%) | 15 (75) | 7 (47) | 0.3 |
Active, n (%) | 0 (0) | 0 (0) | 0.9 |
Pulmonary function test | |||
TLC, %pred (IQR) | 71.5 (67–74) | 95 (88–103) | < 0.0001 |
TLC, L (IQR) | 4.2 (3.6–4.6) | 6.4 (5.3–6.8) | < 0.0001 |
RV, %pred (IQR) | 67.5 (65–70.8) | 99 (93–117) | < 0.0001 |
RV, L (IQR) | 1 (0.9–1.1) | 1.5 (1.4–1.8) | < 0.0001 |
FVC, %pred (IQR) | 65.6 (61.5–74.2) | 99 (84–108) | < 0.0001 |
FVC, L (IQR) | 3.3 (3–3.7) | 5 (4.2–5.4) | < 0.0001 |
FEV1, %pred (IQR) | 74 (63.5–81) | 99 (83–110) | < 0.0001 |
FEV1, L (IQR) | 3.1 (2.4–3.6) | 4.2 (3.4–5.5) | < 0.0001 |
FEV1/FVC, % (IQR) | 78.3 (75.8–83.6) | 82.6 (78.9–85.4) | < 0.0001 |
DLCO, %predicted (IQR) | 50 (38.3–58.8) | 88 (78–91) | < 0.0001 |