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Table 3 Multivariable regressions for CPAP-usage and CPAP-non-adherence as variables-of-interest, summary of significant explanatory-variables including side-effects

From: Mask side-effects are related to gender in long-term CPAP: results from the InterfaceVent real-life study

Variable

CPAP-usage (h/day)

CPAP-non-adherence (< 4 h/day)

Women, N = 413

Men, N = 1071

Women, N = 413

Men, N = 1071

Estimate

95% CI

p-value

Estimate

95% CI

p-value

OR

95% CI

p-value

OR

95% CI

p-value

Demographics

 Age (years)

   

0.02

0.01, 0.03

 < 0.001

   

0.96

0.93, 0.98

 < 0.001

 BMI (kg/m2)

0.04

0.01, 0.07

0.016

0.04

0.02, 0.07

 < 0.001

   

0.93

0.88, 0.99

0.015

 Active smokers

− 0.89

− 1.50, − 0.27

0.005

         

 Presence of partner

         

0.43

0.24, 0.77

0.005

Epworth scale

 ESS (0–24 score)

   

− 0.04

− 0.07, − 0.02

0.001

      

Device

 Current AHIflow (events/h)

         

1.08

1.03, 1.14

0.001

 Treatment duration (years)

   

0.04

0.02, 0.06

 < 0.001

      

 Mean pressure (cmH2O)

0.16

0.06, 0.25

0.002

         

 90th/95th pressure (cmH2O)

   

0.05

0.00, 0.11

0.034

      

Mask

 Mask availability since 2013

   

− 0.30

− 0.53, − 0.07

0.009

   

2.72

1.56, 4.74

 < 0.001

Side-effects

 Partner disturbing leaks (0–10 VAS score)

0.07

0.01, 0.13

0.026

   

0.80

0.68, 0.94

0.007

   

 Harness injury (0–10 VAS score)

   

0.13

0.04, 0.21

0.003

      

 Dry nose (0–10 VAS score)

   

− 0.06

− 0.09, − 0.02

0.004

      

 Dry mouth (0–10 VAS score)

− 0.10

− 0.15, − 0.04

 < 0.001

      

1.08

1.00, 1.16

0.050

  1. Note that for models, explanatory-variables with a p-value < 0.15 at the univariate level were fed into multivariable analyses using stepwise selection. A backward elimination was then applied and only explanatory-variables with a p-value < 0.05 at the multivariable level remain in the definitive models. Bolds variables are statistically significant at the 5% threshold
  2. AHI: Apnea–Hypopnea Index; AHIflow: AHI reported by device; BMI: body mass index; CI: exact confidence interval; CPAP: continuous positive airway pressure; ESS: epworth sleepiness scale; OR: odds ratio; VAS: visual analogue scale.