Table 1 Characteristics of subjects with normal lung function in each cohort
From: CT-based whole lung radiomics nomogram for identification of PRISm from non-COPD subjects
Variables |  | Training Cohort (N = 864) | p-value | Internal Validation Cohort (N = 370) | p-value | External Validation Cohort (N = 247) | p-value | |||
|---|---|---|---|---|---|---|---|---|---|---|
normal spirometry | PRISm | Â | normal spirometry | PRISm | Â | normal spirometry | PRISm | Â | ||
Age |  | 58.6 (12.3) | 63.2 (12.7) | < 0.001 | 58.3 (12.2) | 64.3 (10.4) | < 0.001 | 61.8(0.98) | 61.2(1.3) | 0.949 |
Gender |  |  |  | < 0.001 |  |  | 0.003 |  |  | 0.014 |
| Â | Male | 272 (50.4) | 228 (70.4) | Â | 105 (49.1) | 102 (65.4) | Â | 88(59.9) | 75(75.0) | Â |
| Â | Female | 268 (49.6) | 96 (29.6) | Â | 109 (50.9) | 54 (34.6) | Â | 59(40.1) | 25(25.0) | Â |
Height | Â | 161.4 (7.8) | 163.3 (8) | 0.0006 | 161.3 (8.1) | 172.4 (120.5) | 0.178 | 164.2(0.7) | 165.4(0.9) | 0.309 |
Weight |  | 62.8 (10.7) | 67.5 (12.5) | < 0.001 | 62.3 (9.6) | 66.9 (13.8) | 0.0002 | 63.0(0.8) | 68.3(1.6) | 0.008 |
BMI |  | 24 (3.2) | 25.3 (4.2) | < 0.001 | 23.9 (2.8) | 25 (4.7) | 0.005 | 23.4(0.3) | 24.8(0.5) | 0.026 |
Smoking status | Â | Â | Â | 0.0003 | Â | Â | 0.0002 | Â | Â | 0.567 |
| Â | Current Smoker | 84 (15.6) | 67 (20.7) | Â | 28 (13.1) | 44 (28.2) | Â | 74(50.3) | 44(44.0) | Â |
| Â | Former Smoker | 36 (6.7) | 43 (13.3) | Â | 17 (7.9) | 19 (12.2) | Â | 30(20.4) | 21(21.0) | Â |
| Â | Non-smoker | 420 (77.8) | 214 (66.0) | Â | 169 (79.0) | 93 (59.6) | Â | 43(29.3) | 35(35.0) | Â |