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Table 4 Overall and sex- and age-specific incidence rates and HR for COPD in the NTM-PD and matched control cohorts using a nationwide cohort dataset

From: Risk of incident chronic obstructive pulmonary disease during longitudinal follow-up in patients with nontuberculous mycobacterial pulmonary disease

 

Cases

Incidence rate

(/100,000 PY)

Sub-distribution hazard ratio (95% CI)

Unadjusted HR

Adjusted HR*

Overall

    

 Matched control cohort

28

5.3

Reference

Reference

 NTM-PD cohort

24

14.8

2.10 (1.30–3.38)

2.04 (1.21–3.42)

Sex

    

 Male

    

  Matched control cohort

16

8.0

Reference

Reference

  NTM-PD cohort

6

10.6

1.05 (0.48–2.30)

0.94 (0.41–2.13)

 Female

    

  Matched control cohort

12

3.7

Reference

Reference

  NTM-PD cohort

18

17.1

3.50 (1.84–6.67)

3.55 (1.65–7.62)

Age

    

 < 60 years

    

  Matched control cohort

8

2.8

Reference

Reference

  NTM-PD cohort

14

15.9

3.71 (1.64–8.37)

1.93 (0.73–5.07)

 ≥ 60 years

    

  Matched control cohort

20

8.1

Reference

Reference

  NTM-PD cohort

10

13.5

1.49 (0.80–2.75)

1.68 (0.86–3.27)

  1. *Adjusted for BMI and Charlson comorbidity index
  2. The smoking status was not adjusted for because it did not differ significantly between the two groups
  3. Abbreviations: HR, hazard ratio; COPD, chronic obstructive pulmonary disease; NTM-PD, nontuberculous mycobacterial pulmonary disease; PY, per year; CI, confidence interval