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Fig. 5 | Respiratory Research

Fig. 5

From: Recombinant thrombomodulin and recombinant antithrombin attenuate pulmonary endothelial glycocalyx degradation and neutrophil extracellular trap formation in ventilator-induced lung injury in the context of endotoxemia

Fig. 5

Changes in peak inspiratory pressure and dynamic lung compliance. (A) Hourly changes in PIP from the start of mechanical ventilation to 4 h (N = 6). PIP at the end of mechanical ventilation was higher in the HTV group than in the rTMAT group (*P < 0.05). PIP at the beginning of mechanical ventilation was lower than at any other time point in all groups. PIP at 4 h was higher than that at 1 h in the HTV group (+P < 0.01). (B) Hourly changes in DLP from the start of mechanical ventilation to 4 h (N = 6). There was no difference in DLP between groups at any time point. DLP was higher at the beginning of mechanical ventilation than at any other time point in all groups. DLP at 4 h was lower than that at 1 h in the HTV group (#P < 0.05). PIP = peak inspiratory pressure; DLP = dynamic lung compliance; HTV = high tidal volume ventilation

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Respiratory Research

ISSN: 1465-993X

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