Skip to main content
Fig. 5 | Respiratory Research

Fig. 5

From: Unraveling the Mfn2-Warburg effect nexus: a therapeutic strategy to combat pulmonary arterial hypertension arising from catch-up growth after IUGR

Fig. 5

Mfn2 overexpression reversed the Warburg effect in PASMC of RC groups. a, Oxygen consumption rate of PASMCs. b, Quantitative statistical analysis of OCR. c, extracellular acidification rate of PASMCs. d, Quantitative statistical analysis of ECAR. OCR, oxygen consumption rate; ECAR, extracellular acidification rate; Ad-EV, control adenovirus; Ad-Mfn2, recombinant adenovirus encoding Mfn2, RC + Ad-Ev, RC group PASMCs transfected with control adenovirus; RC + Ad-Mfn2, RC group PASMCs transfected with recombinant adenovirus encoding Mfn2. All data throughout the figures represent the mean ± SEM and analyzed by one-way analysis of variance (ANOVA) and Newman-keuls post-hoc test. * p < 0.05 vs. Con + Ad-EV, ** p < 0.01 vs. Con + Ad-EV, ## p < 0.01 vs. RC + Ad-EV. ### p < 0.001 vs. RC + Ad-EV

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us