Table 3 Additional immunohistochemical findings (intensity score in alveolar walls and bronchiolar epithelium)
|  | COPD n = 22 | Smoker controls (SC) n = 21 | Non-smoker controls (nSC) n = 15 | p-value |
|---|---|---|---|---|
IRF3 score alveolar wall | 0 [0–1] | 0 [0–1] | 0 [0–0] | 0.577 |
IRF3 score epithelium | 0 [0–2] | 0 [0–1] | 0 [0–0] | 0.965 |
MDA5 score alveolar wall | 1 [0–2] | 1 [1–2] | 1 [0–1] | 0.211 |
MDA5 score epithelium | 0 [0–2] | 0 [0–2] | 0 [0–2] | 0.444 |
IFNAR1 score alveolar wall | 0 [0–1] | 0 [0–1] | 0 [0–1] | 0.987 |
IFNAR1 score epithelium | 1 [0–2] | 1 [0–1] | 1 [0–1] | 0.998 |
IFNAR2 score alveolar wall | 0 [0–0] | 0 [0–1] | 0 [0–0] | 0.905 |
IFNAR2 score epithelium | 1 [0–2] | 1 [0–2] | 1 [0–2] | 0.542 |