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Fig. 3 | Respiratory Research

Fig. 3

From: Expression of human Interferon Regulatory Factor 3 (IRF-3) in alveolar macrophages relates to clinical and functional traits in COPD.

Fig. 3

Bivariate scattergram reporting the relationship between FEV1 (%pred.) and the percentage of IRF3+ macrophages (A) or lymphocytes NK (C) in COPD patients stratified for the presence (black dots) or the absence (white dots) of chronic bronchitis (CB). Fisher analysis showed a significant association between CB presence, airflow impairment and low IRF3 expression. P-value have been calculated by Fisher’s exact test 4 × 2 contingency table. (B) Boxplot illustrating the percentage of IRF3+ macrophages in patients with COPD stratified on the presence/absence of chronic bronchitis (CB+/-) and at least one acute exacerbation during the previous year (AE +/-) (AE + CB + n = 6; AE + CB- n = 6; AE-CB + n = 3; AE-CB- n = 5). Solid line represents the median; bottom and top of the boxes are the 25th and 75th percentiles; brackets correspond to the 10th and the 90th percentiles

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Respiratory Research

ISSN: 1465-993X

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