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Fig. 8 | Respiratory Research

Fig. 8

From: Vitamin D ameliorates particulate matter induced mitochondrial damages and calcium dyshomeostasis in BEAS-2B human bronchial epithelial cells

Fig. 8

A schematic illustration of the advantageous function of 1,25(OH)2D3 in enhancing epithelial defense against PM-induced mitochondrial ROS damages. Supplementation with 1,25(OH)2D3 ameliorates PM-induced mitochondrial malfunctions, calcium dyshomeostasis and inflammation by regulating mitochondrial ROS homeostasis through enhancing antioxidant responses in BEAS-2B cells. PM-induced detrimental impacts on mitochondria were shown in red-color texts or arrows. The beneficial regulation of 1,25(OH)2D3 were shown in blue-color texts or arrows

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