Cobalt exposure and pulmonary function reduction in chronic obstructive pulmonary disease patients: the mediating role of club cell secretory protein

Table 2 Associations between blood co and pulmonary function parameters in COPD patients

Variables	Continues blood Co (ppm)		Tertiles of blood Co (ppm)			P trend
Variables	Continues blood Co (ppm)	P	Tertile 1 (<0.635)	Tertile 2 (0.635 ~ 1.230)	Tertile 3 (>1.230)	P trend
N	771		257	257	257
FVC (L)	-0.598 (-0.771, -0.425)	0.001	0 (Ref)	0.228 (-0.102, 0.559)	-0.637 (-0.845, -0.328)	0.013
FEV1 (L)	-0.465 (-0.627, -0.303)	0.001	0 (Ref)	0.446 (0.106, 0.786)	-0.143 (-0.460, 0.175)	0.021
FEV1/FVC (%)	-6.540 (-9.598, -3.481)	0.001	0 (Ref)	7.268 (1.405, 13.132)	-1.235 (-6.642, 4.172)	0.625
FEV1 (%)	-14.013 (-19.770, -8.257)	0.011	0(Ref)	-13.768 (-24.795, -2.740)	-19.282 (-29.527, -9.038)	0.002

Models were adjusted for age, gender, enrolled season, smoking status, smoking amount, self-coking, hypertension, coronary disease, and ICS usage
Bold values indicate statistical significance

ISSN: 1465-993X