Fig. 1

Characterization of the asthmatic model. BALB/c mice were exposed to Dermatophagoides pteronyssinus (DerP) extract or PBS at the indicated days (A). Two-, eight-, fourteen- and twenty-one-days post exposure, bronchoalveolar lavage (B and C), lung function (D) and bronchial smooth muscle remodeling (E) were assessed (n = 5 mice per group at days 2 and 8, n = 6 mice per group at days 14 and 21, from two independent experiments). Pictures in E are representative staining of α-SMA in PBS and DerP mice at day 21