Skip to main content
Fig. 3 | Respiratory Research

Fig. 3

From: Levosimendan mediates the BMP/Smad axis through upregulation of circUSP34-targeted miR-1298 to alleviate pulmonary hypertension

Fig. 3

CircUSP34 regulates miR-1298. (A) Circular RNA interactome predicted the potential binding site of circUSP34 and miR-1298. (B) Dual luciferase assay detected the interaction between miR-1298 and circUSP34. (C) RIP assay was used to test the ability of Ago2 to enrich for circUSP34 and miR-1298. (D) qRT-PCR assay was employed to examine miR-1298 expression in PASMCs under knockdown circUSP34 or overexpression of circUSP34. (E) qRT-PCR assay was applied to check miR-1298 expression in PASMCs under different treatment conditions. Data are displayed for three individual experiments with mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us