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Fig. 2 | Respiratory Research

Fig. 2

From: Levosimendan mediates the BMP/Smad axis through upregulation of circUSP34-targeted miR-1298 to alleviate pulmonary hypertension

Fig. 2

Lev inhibits cell proliferation, migration and promotes apoptosis in hypoxia-treated PASMCs through upregulation of circUSP34. (A) qRT-PCR assay was employed to examine circUSP34 expression. (B) The expression of circUSP34 in PASMCs under different treatment conditions was detected by qRT-PCR assay. (C) Cell proliferation ability was examined by CCK-8. (D) Ki-67 expression in PASMCs was measured by IF. (E) Cell migration ability of PASMCs was assayed by cell scratch assay. (F) Apoptosis of PASMCs was tested by flow cytometry. Data are displayed for three individual experiments with mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

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Respiratory Research

ISSN: 1465-993X

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