Fig. 2

Cumulative incidence plot of exacerbations requiring hospitalization and all-cause mortality in propensity score matched patient groups treated with ICS delivered by low and high climate impact inhalers. Patients were propensity score matched 1:1 by age, gender, tobacco exposure, exacerbations requiring hospitalization, MRC, BMI, FEV1% and daily dosage of inhaled corticosteroids in the year before entry date as well as entry year. The primary outcome is a composite outcome of exacerbations requiring hospitalization (admissions diagnosed as DJ44 Chronic obstructive pulmonary disease and all belonging subcodes) and all-cause mortality