Fig. 2

CS exposure induces distinct transcriptomic remodelling in BMDMs compared to AMs. A Volcano plot of AM DEGs in CS-exposed mice (n = 4) compared to RA (n = 4). B Biological processes associated with AM CS-induced downregulated DEGs. C Canonical pathways produced from Ingenuity Pathway Analysis enriched in AM CS-induced DEGs and their activation z-scores. D Comparison of Log2 fold change values in BMDMs and AMs from CS exposed mice compared to RA, with significant DEGs common to both cell types highlighted. E Heat map comparing activation z-score of canonical pathways induced by CS in BMDMs and AMs