Table 4 Clinical characteristics, HR-QoL and asthma control in patients with exacerbation asthma based on the presence or absence of SAD

Age, y

39.5 (28-50.75)

55 (50–62)

-6.78

Sex (% female)

62.5

55.6

-

Body mass index, kg/m²

25.1(23-26.7)

26.1(24–28)

-2.094

Smoking History(%)

Current or former smokers > 10 pack-y (%)

67

95

-

Pack-year

23.5 (2.75–28.5)

25 (16–30)

-0.786

Fractional exhaled nitric oxide, ppb

27.5 (14–46)

34 (19–74)

-2.007

Blood eosinophil count, µL

0.19 (0.09–0.36)

0.2 (0.08–0.5)

-0.938

Respiratory function (%)

FEV₁ (%)

103.58(94.63-111.05)

74.92(57.8–90)

-8.85

FVC (%)

104.71(99.04-116.32)

98(83.9–110)

-3.649

FEV₁/FVC (%)

98.55(96.16–103)

82(65.76-88)

-10.083

FEF₇₅

99.6 (91.25–115.5)

52 (30–73)

-10.31

FEF₅₀

79.6 (74.48–90.63)

33 (19–50)

-11.168

FEF₂₅

58.15 (49.33–72.08)

22 (13–33)

-10.398

FEF_{25 − 75}

74.25 (67.78–83.88)

30 (17-44.8)

-10.987

Mini-AQLQ

total

3.8 (3.4–4.2)

3.4 (2.1–3.9)

-2.65

symptoms

3.6 (3.4-4)

3.2 (2–4)

-2.533

activities

3.8 (3.3–4.3)

3.5 (2.5-4)

-2.767

emotional

3.7 (3-4.6)

3.3 (2–4)

-2.142

environmental

3.7 (3.3–4.3)

3.3 (2.3-4)

-2.673

Asthma control test score

18 (16.25-20)

12 (10–16)

-7.895

> 2 acute exacerbation (%)

0

50.3

-