Skip to main content

Table 3 Top 15 proteins identified from endogenous peptides whose degradation was associated with FEV1pp

From: Novel approach to exploring protease activity and targets in HIV-associated obstructive lung disease using combined proteomic-peptidomic analysis

Protein

UniProt ID

Mean FEV1pp (Present)

Mean FEV1pp (Absent)

P-Value

FDR

Alpha-enolase

P06733

53.9625

91.8787

0.0004

0.0247

Gelsolin

P06396

45.4126

90.3352

0.0008

0.0247

Histone H4

P62805

61.1725

91.9697

0.0009

0.0247

Tubulin beta-4B chain

P68371

55.6507

90.7484

0.0022

0.0414

Histone H2B type 2-F

Q5QNW6

56.8110

91.3487

0.0036

0.0414

Tubulin alpha-1A chain

Q71U36

64.6865

91.1127

0.0045

0.0414

Glyceraldehyde-3-phosphate dehydrogenase

P04406

65.3887

91.5802

0.0046

0.0414

Myosin-9

P35579

61.5678

88.5792

0.0046

0.0414

Aldehyde dehydrogenase, dimeric NADP-preferring

P30838

61.6220

91.1401

0.0046

0.0414

Glutathione S-transferase P

P09211

61.7737

91.1076

0.0054

0.0414

Vimentin

P08670

78.8246

96.0831

0.0054

0.0414

Isoform A2 of Heterogeneous nuclear ribonucleoproteins A2/B1

P22626-2

66.1016

89.0858

0.0062

0.0425

Galectin-3

P17931

70.2732

92.4552

0.0066

0.0425

Parkinson disease protein 7

Q99497

62.8499

90.8770

0.0074

0.0442

Basic salivary proline-rich protein 1

P04280

66.1060

90.7664

0.0087

0.0486