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Table 1 Demographics of study participant cohort.

From: Novel approach to exploring protease activity and targets in HIV-associated obstructive lung disease using combined proteomic-peptidomic analysis

 

OLD (N = 25)

Without OLD (N = 26)

Total (N = 51)

Sex

 Male

19 (76.0%)

18 (69.2%)

37 (72.5%)

 Female

6 (24.0%)

8 (30.8%)

14 (27.5%)

Age

 Mean (SD)

60.0 (8.47)

53.8 (7.30)

56.8 (8.42)

 Median [min, max]

58.0 [44.0, 80.0]

54.0 [42.0, 76.0]

56.0 [42.0, 80.0]

Ethnicity

 Black, Non-Hispanic

16 (64.0%)

12 (46.2%)

28 (54.9%)

 White, Hispanic/Latino

9 (36.0%)

13 (50.0%)

22 (43.1%)

 Asian/pacific islander

0 (0%)

1 (3.8%)

1 (2.0%)

Smoking status

 Former

9 (36.0%)

7 (26.9%)

16 (31.4%)

 Never

3 (12.0%)

5 (19.2%)

8 (15.7%)

 Yes

13 (52.0%)

14 (53.8%)

27 (52.9%)

Pack years

 Mean (SD)

31.1 (28.9)

15.2 (13.7)

23.0 (23.7)

 Median [min, max]

29.2 [0, 120]

13.6 [0, 38.0]

17.0 [0, 120]

Receiving antiretroviral treatment

 Yes

23 (92.0%)

24 (92.3%)

47 (92.2%)

 No

2 (8.0%)

2 (7.7%)

4 (7.8%)

FEV1-percent-predicted

 Mean (SD)

67.5 (16.1)

104 (11.2)

85.9 (22.8)

 Median [min, max]

68.2 [21.0, 90.4]

102 [81.3, 128]

87.1 [21.0, 128]

FEV1

 Mean (SD)

2.05 (0.600)

3.25 (0.746)

2.66 (0.905)

 Median [min, max]

2.00 [0.650, 3.29]

3.08 [1.95, 4.77]

2.59 [0.650, 4.77]

FEV1/FVC

 Mean (SD)

0.553 (0.115)

0.795 (0.0567)

0.676 (0.151)

 Median [min, max]

0.588 [0.293, 0.679]

0.789 [0.689, 0.905]

0.689 [0.293, 0.905]

DLCO-percent-predicted

 Mean (SD)

70.5 (26.5)

76.6 (23.1)

73.7 (24.7)

 Median [min, max]

57.1 [36.3, 139]

74.5 [14.4, 117]

73.3 [14.4, 139]

M issing

6 (24.0%)

5 (19.2%)

11 (21.6%)

Viral load

 < 50 copies

12 (48.0%)

18 (69.2%)

30 (58.8%)

 > 50 copies

1 (4.0%)

3 (11.5%)

4 (7.8%)

Missing

12 (48.0%)

5 (19.2%)

17 (33.3%)

  1. FEV forced expiratory volume in 1-s, FVC forced vital capacity, DLCO diffusing capacity of lung for carbon monoxide