Fig. 2
From: The role of extracellular traps released by neutrophils, eosinophils, and macrophages in asthma
The role of NETs in asthmatic airway inflammation. NETs are involved in asthmatic airway inflammation by mediating direct airway epithelial barrier injury, promoting the secretion of cytokines from epithelial cells, enhancing the recruitment of T cells and the secretion of TNF-α and IL-6 by T cells. TNF-α, tumor necrosis factor-α; IL-1/6/8/25/33, interleukin-1/6/8/25/33; TSLP, thymic stromal lymphopoietin; CXCL1/2/8, CXC motif chemokine ligand 1/2/8