Table 1 Baseline characteristics and pulmonary function of patients with uncontrolled asthma caused by dyspnea

n

17

Characteristics of the patients

 Age (y)

60.6 (4.6)

 Sex (male:female), n

4:13

 BMI (kg/m²)

24.9 (1.2)

 Smoking status (smoker:never smoker), n

7:10

 Atopy (atopy:non-atopy), n

11:6

 Blood eosinophil count (cells/uL)

354.4 (95.6)

 Serum IgE (U/L)

730.9 (260.2)

Thearpeutic evaluation

 AHQ

32.8 (3.9)

12.7 (2.4)

< 0.001**

 ACT

19.6 (0.7)

24.2 (0.2)

< 0.001**

Spirometry

 FEV1 (L)

2.28 (0.22)

1.96 (0.24)

2.26 (0.23)

< 0.001**

 < 0.001**

 %FEV1 predicted

95.6 (4.5)

81.3 (4.5)

96.2 (4.6)

< 0.001**

 < 0.001**

 %FVC predicted

99.9 (4.3)

87.8 (3.9)

102.0 (4.4)

< 0.001**

 < 0.001**

 FEV1/FVC ratio

78.6 (2.4)

75.1 (2.5)

77.2 (2.5)

0.021*

0.21

 %MMEF predicted

67.6 (6.8)

48.1 (7.8)

64.9 (7.7)

< 0.001**

0.001**

 %PEF predicted

100.4 (5.5)

81.7 (6.5)

98.7 (6.6)

< 0.001**

 < 0.001**

Impulse oscillometry

 R5, (kPa/L/s)

0.32 (0.01)

0.39 (0.02)

0.30 (0.01)

0.003**

0.001**

 R20 (kPa/L/s)

0.26 (0.01)

0.32 (0.02)

0.25 (0.01)

0.005**

0.001**

 R5–R20, kPa/L/s

0.06 (0.01)

0.08 (0.02)

0.06 (0.01)

0.03*

0.017*

 X5 (kPa/L/s)

− 0.12 (0.01)

− 0.19 (0.03)

− 0.13 (0.01)

0.013*

0.014*

 Fres ( Hz)

13.9 (1.2)

16.0 (1.4)

13.9 (1.2)

0.002**

0.004**

 AX (kPa/L)

0.51 (0.10)

1.02 (0.21)

0.57 (0.11)

0.004**

0.004**