Fig. 2

Altered cancer-related proteins in LC patients. a PLS-DA score plots of differentially expressed proteins (DEPs) in HC and LC groups. b Heatmap of DEPs between HC and LC groups (FC > 1·5 or < 0·67, adjust P < 0·05). c Volcano plot showing the top 10 upregulated and downregulated proteins with the greatest differences between HC and LC groups. d GO analysis of DEPs between HC and LC groups. e KEGG analysis of DEPs between HC and LC groups. Top pathways are shown in this figure