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Fig. 5 | Respiratory Research

Fig. 5

From: Therapeutic efficacy of thrombin-preconditioned mesenchymal stromal cell-derived extracellular vesicles on Escherichia coli-induced acute lung injury in mice

Fig. 5

Intratracheal administration of thMSC-EVs attenuated tissue injury in E. coli-induced ALI mice. (A) Representative microscopic images of lung tissues of each group. (Original magnification;\(\:\:\times\:\:\)40, scale bars; 200 μm) (B) Scored histological grades of alveolar congestion, alveolar hemorrhage, leukocyte infiltration, and alveolar wall thickening in lung tissue. n = 10, 14, and 19 in NC, ECS, and EME groups, respectively. Data are presented as a box and whisker plot. Whiskers represent the min and max. **, p < 0.01 vs. NC; #, p < 0.05 vs. ECS; ##, p < 0.01 vs. ECS. One-way ANOVA post hoc Tukey was used. NC, normal control; ECS, E. coli-induced ALI control group; EME, thMSC-EVs treatment group after E. coli-induced ALI

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Respiratory Research

ISSN: 1465-993X

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