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Fig. 3 | Respiratory Research

Fig. 3

From: Therapeutic efficacy of thrombin-preconditioned mesenchymal stromal cell-derived extracellular vesicles on Escherichia coli-induced acute lung injury in mice

Fig. 3

Anti-inflammatory effect of thMSC-EVs in LPS-stimulated RAW 264.7 cells. (A) Study design of the LPS-stimulated RAW 264.7 cells ALI in vitro model. (B) The levels of pro-inflammatory cytokines IL-1β, IL-6, CCL-2, and MMP-9 were measured using ELISA. n = 4, 6, 6 in the NC, LPS Ctrl, and LPS + thMSC-EVs groups, respectively. Data are presented as box and whisker plot. whiskers represent the min and max. **, p < 0.01 vs. NC; ##, p < 0.01 vs. LPS Ctrl group. One-way analysis of variance (ANOVA) post hoc Tukey analysis was used. NC, normal control; LPS Ctrl, LPS control group; LPS + thMSC-EVs, thMSC-EVs treated group

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Respiratory Research

ISSN: 1465-993X

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